William was born in Wilkes County, Georgia, and lived there through his childhood. He attended the Jefferson Medical College of Thomas Jefferson University in Philadelphia, Pennsylvania, graduating in 1876.
He married Daisy Eugenia Hance on 26 Oct 1882 in Oglethorpe County, Georgia. They had 8 children, and lived in Atlanta, Georgia, after 1893.
William practiced medicine in Wilkes County, and in Atlanta, but later gave up his practice to devote his entire time to a hardware business he also operated.
William is interred at Greenwood Cemetery in Atlanta, Georgia.
William Martin Spratlin (1854-1928) is 2nd cousin 5x removed of MKS in the Spratlin branch.
 Ancestry.com member gototea (photograph).